Regulation of the transcriptional program by DNA methylation during human αβ T-cell development

Thymocyte differentiation is a complex process involving well-defined sequential developmental stages that ultimately result in the generation of mature T-cells. In this study, we analyzed DNA methylation and gene expression profiles at successive human thymus developmental stages. Gain and loss of...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Rodriguez, Ramon M., Suarez-Alvarez, Beatriz, Mosén-Ansorena, David, García-Peydró, Marina, Fuentes, Patricia, García-León, María J., Gonzalez-Lahera, Aintzane, Macias-Camara, Nuria, Toribio, María L., Aransay, Ana M., Lopez-Larrea, Carlos
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
Предметы:
Gene regulation, Chromatin and Epigenetics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333391/
https://ncbi.nlm.nih.gov/pubmed/25539926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1340
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