A promoter DNA demethylation landscape of human hematopoietic differentiation

Global mechanisms defining the gene expression programs specific for hematopoiesis are still not fully understood. Here, we show that promoter DNA demethylation is associated with the activation of hematopoietic-specific genes. Using genome-wide promoter methylation arrays, we identified 694 hematop...

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Autori principali: Calvanese, Vincenzo, Fernández, Agustín F., Urdinguio, Rocío G., Suárez-Alvarez, Beatriz, Mangas, Cristina, Pérez-García, Vicente, Bueno, Clara, Montes, Rosa, Ramos-Mejía, Verónica, Martínez-Camblor, Pablo, Ferrero, Cecilia, Assenov, Yassen, Bock, Christoph, Menendez, Pablo, Carrera, Ana Clara, Lopez-Larrea, Carlos, Fraga, Mario F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Gene Regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245917/
https://ncbi.nlm.nih.gov/pubmed/21911366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr685
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