A promoter DNA demethylation landscape of human hematopoietic differentiation

Global mechanisms defining the gene expression programs specific for hematopoiesis are still not fully understood. Here, we show that promoter DNA demethylation is associated with the activation of hematopoietic-specific genes. Using genome-wide promoter methylation arrays, we identified 694 hematop...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Calvanese, Vincenzo, Fernández, Agustín F., Urdinguio, Rocío G., Suárez-Alvarez, Beatriz, Mangas, Cristina, Pérez-García, Vicente, Bueno, Clara, Montes, Rosa, Ramos-Mejía, Verónica, Martínez-Camblor, Pablo, Ferrero, Cecilia, Assenov, Yassen, Bock, Christoph, Menendez, Pablo, Carrera, Ana Clara, Lopez-Larrea, Carlos, Fraga, Mario F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2012
Aiheet:
Gene Regulation, Chromatin and Epigenetics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245917/
https://ncbi.nlm.nih.gov/pubmed/21911366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr685
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