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Functional DNA demethylation is accompanied by chromatin accessibility
DNA methylation inhibitors such as 5-aza-2′-deoxycytidine (5-Aza-CdR) are currently used for the treatment of myelodysplastic syndrome. Although global DNA demethylation has been observed after treatment, it is unclear to what extent demethylation induces changes in nucleosome occupancy, a key deter...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627572/ https://ncbi.nlm.nih.gov/pubmed/23408854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt077 |
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