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Establishment of active chromatin structure at enhancer elements by mixed-lineage leukemia 1 to initiate estrogen-dependent gene expression

A number of genome-wide analyses have revealed that estrogen receptor α binding to and regulation of its target genes correlate with binding of FOXA1, a pioneer factor, to nearby DNA sites in MCF-7 breast cancer cells. The enhancer element-specific histone H3K4me1/2 mark is enriched at the specific...

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Autors principals: Jeong, Kwang Won, Andreu-Vieyra, Claudia, You, Jueng Soo, Jones, Peter A., Stallcup, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936730/
https://ncbi.nlm.nih.gov/pubmed/24288367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1236
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