Endosomal aspartic proteinases are required for invariant-chain processing.

Immunogenic peptides are displayed in the context of class II histocompatibility proteins on the surface of antigen-presenting cells. Class II alpha and beta subunits bind the invariant chain (I-chain), a transmembrane glycoprotein which must dissociate prior to peptide presentation. Proteolytic rel...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Marić, M A, Taylor, M D, Blum, J S
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1994
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43332/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8134367/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.6.2171
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