Endosomal aspartic proteinases are required for invariant-chain processing.
Immunogenic peptides are displayed in the context of class II histocompatibility proteins on the surface of antigen-presenting cells. Class II alpha and beta subunits bind the invariant chain (I-chain), a transmembrane glycoprotein which must dissociate prior to peptide presentation. Proteolytic rel...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43332/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8134367/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.6.2171 |
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