Unveiling cytochrome P450 enzymes that catalyze steroid side-chain cleavage in bacteria

Abstract Steroids are among the most valuable and widely used pharmaceuticals. The cholesterol side-chain cleavage enzyme (P450scc) is critical for steroid metabolism and hormone biosynthesis. While mammalian eukaryotic P450scc enzymes are well-characterized, bacterial counterparts remain underexplo...

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Autors principals:	Wenya Tian, Guangzheng Wei, Borui Duan, Haidong Peng, Huanhuan Liu, Mengmeng Zheng, Zhi Lin, Zixin Deng, Zhengyu Zhang, Xudong Qu
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-12-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-025-67278-3
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