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Single-Stranded γPNAs for In Vivo Site-Specific Genome Editing via Watson-Crick Recognition
Triplex-forming peptide nucleic acids (PNAs) facilitate gene editing by stimulating recombination of donor DNAs within genomic DNA via site-specific formation of altered helical structures that further stimulate DNA repair. However, PNAs designed for triplex formation are sequence restricted to homo...
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| Publicado no: | Curr Gene Ther |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333085/ https://ncbi.nlm.nih.gov/pubmed/25174576 |
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