Galectin-3 mediates bone marrow microenvironment-induced drug resistance in acute leukemia cells via Wnt/β-catenin signaling pathway

BACKGROUND: Acute leukemia is currently the major cause of death in hematological malignancies. Despite the rapid development of new therapies, minimal residual disease (MRD) continues to occur and leads to poor outcomes. The leukemia niche in the bone marrow microenvironment (BMM) is thought to be...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Hu, Kaimin, Gu, Yanjun, Lou, Lixia, Liu, Lizhen, Hu, Yongxian, Wang, Binsheng, Luo, Yi, Shi, Jimin, Yu, Xiaohong, Huang, He
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332970/
https://ncbi.nlm.nih.gov/pubmed/25622682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0099-8
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