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The bone marrow microenvironment and leukemia: biology and therapeutic targeting
Multiple studies have demonstrated that interaction with the bone marrow stromal microenvironment contributes to the survival of leukemia cells. One explanation for this phenomenon is the interaction between the cell surface receptors CXCR4 and CXCL12. Through CXCL12/CXCR4-mediated chemotaxis, leuke...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131221/ https://ncbi.nlm.nih.gov/pubmed/21668393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/ehm.11.30 |
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