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The bone marrow microenvironment and leukemia: biology and therapeutic targeting

Multiple studies have demonstrated that interaction with the bone marrow stromal microenvironment contributes to the survival of leukemia cells. One explanation for this phenomenon is the interaction between the cell surface receptors CXCR4 and CXCL12. Through CXCL12/CXCR4-mediated chemotaxis, leuke...

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Detalhes bibliográficos
Main Authors: Sison, Edward Allan R, Brown, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131221/
https://ncbi.nlm.nih.gov/pubmed/21668393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/ehm.11.30
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