Galectin-3 mediates bone marrow microenvironment-induced drug resistance in acute leukemia cells via Wnt/β-catenin signaling pathway

BACKGROUND: Acute leukemia is currently the major cause of death in hematological malignancies. Despite the rapid development of new therapies, minimal residual disease (MRD) continues to occur and leads to poor outcomes. The leukemia niche in the bone marrow microenvironment (BMM) is thought to be...

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Bibliografische gegevens
Gepubliceerd in:J Hematol Oncol
Hoofdauteurs: Hu, Kaimin, Gu, Yanjun, Lou, Lixia, Liu, Lizhen, Hu, Yongxian, Wang, Binsheng, Luo, Yi, Shi, Jimin, Yu, Xiaohong, Huang, He
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332970/
https://ncbi.nlm.nih.gov/pubmed/25622682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0099-8
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