Differential regulation of myeloid leukemias by the bone marrow microenvironment

Like their normal hematopoietic stem cell counterparts, leukemia stem cells (LSC) in chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML) are presumed to reside in specific niches in the bone marrow microenvironment (BMM)(1), and may be the cause of relapse following chemotherapy.(2)...

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Autores principales: Krause, Daniela S., Fulzele, Keertik, Catic, Andre, Sun, Chia Chi, Dombkowski, David, Hurley, Michael P., Lezeau, Sanon, Attar, Eyal, Wu, Joy Y., Lin, Herbert Y., Divieti-Pajevic, Paola, Hasserjian, Robert P., Schipani, Ernestina, Van Etten, Richard A., Scadden, David T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827980/
https://ncbi.nlm.nih.gov/pubmed/24162813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3364
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