Differential regulation of myeloid leukemias by the bone marrow microenvironment

Like their normal hematopoietic stem cell counterparts, leukemia stem cells (LSC) in chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML) are presumed to reside in specific niches in the bone marrow microenvironment (BMM)(1), and may be the cause of relapse following chemotherapy.(2)...

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Autori principali: Krause, Daniela S., Fulzele, Keertik, Catic, Andre, Sun, Chia Chi, Dombkowski, David, Hurley, Michael P., Lezeau, Sanon, Attar, Eyal, Wu, Joy Y., Lin, Herbert Y., Divieti-Pajevic, Paola, Hasserjian, Robert P., Schipani, Ernestina, Van Etten, Richard A., Scadden, David T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827980/
https://ncbi.nlm.nih.gov/pubmed/24162813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3364
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