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Vitamin K antagonism impairs the bone marrow microenvironment and hematopoiesis

Vitamin K antagonists (VKAs) have been used in 1% of the world’s population for prophylaxis or treatment of thromboembolic events for 64 years. Impairment of osteoblast function and osteoporosis has been described in patients receiving VKAs. Given the involvement of cells of the bone marrow microenv...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Verma, Divij, Kumar, Rahul, Pereira, Raquel S., Karantanou, Christina, Zanetti, Costanza, Minciacchi, Valentina R., Fulzele, Keertik, Kunz, Kathrin, Hoelper, Soraya, Zia-Chahabi, Sara, Jabagi, Marie-Joëlle, Emmerich, Joseph, Dray-Spira, Rosemary, Kuhlee, Franziska, Hackmann, Karl, Schroeck, Evelin, Wenzel, Philip, Müller, Stefan, Filmann, Natalie, Fontenay, Michaela, Pajevic, Paola Divieti, Krause, Daniela S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022447/
https://ncbi.nlm.nih.gov/pubmed/31003999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2018874214
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