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Influence of Leaving-Group Electronic Effect on α-Chymotrypsin: Catalytic Constants of Specific Substrates

Rate constants and binding constants for the α-chymotrypsin-catalyzed hydrolysis of N-acetyltyrosine, tryptophan, and phenylalanine anilides are presented. Both k(cat) and K(m) are independent of electronic effects in the substrate over a range of 9.8 orders of magnitude (as measured by pK of the le...

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Bibliografische gegevens
Hoofdauteurs: Philipp, Manfred, Pollack, Ralph M., Bender, Myron L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1973
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC433295/
https://ncbi.nlm.nih.gov/pubmed/16592059
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