Influence of Leaving-Group Electronic Effect on α-Chymotrypsin: Catalytic Constants of Specific Substrates

Rate constants and binding constants for the α-chymotrypsin-catalyzed hydrolysis of N-acetyltyrosine, tryptophan, and phenylalanine anilides are presented. Both k(cat) and K(m) are independent of electronic effects in the substrate over a range of 9.8 orders of magnitude (as measured by pK of the le...

全面介紹

書目詳細資料

發表在:	Proc Natl Acad Sci U S A
Principais autores:	Philipp, Manfred, Pollack, Ralph M., Bender, Myron L.
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1973
主題:	Biological Sciences: Biochemistry
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433295/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16592059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.2.517
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!