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Emerging links between E2F control and mitochondrial function

The family of E2F transcription factors is the key downstream target of the Retinoblastoma tumor suppressor protein (pRB), which is frequently inactivated in human cancer. E2F is best known for its role in cell cycle regulation and triggering apoptosis. However, E2F binds to thousands of genes and,...

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Detalles Bibliográficos
Publicado en:Cancer Res
Autores principales: Benevolenskaya, Elizaveta V, Frolov, Maxim V
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332890/
https://ncbi.nlm.nih.gov/pubmed/25634216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2173
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