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Emerging links between E2F control and mitochondrial function

The family of E2F transcription factors is the key downstream target of the Retinoblastoma tumor suppressor protein (pRB), which is frequently inactivated in human cancer. E2F is best known for its role in cell cycle regulation and triggering apoptosis. However, E2F binds to thousands of genes and,...

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Dettagli Bibliografici
Pubblicato in:Cancer Res
Autori principali: Benevolenskaya, Elizaveta V, Frolov, Maxim V
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332890/
https://ncbi.nlm.nih.gov/pubmed/25634216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2173
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