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Context-Dependent Requirement for dE2F during Oncogenic Proliferation

The Hippo pathway negatively regulates the cell number in epithelial tissue. Upon its inactivation, an excess of cells is produced. These additional cells are generated from an increased rate of cell division, followed by inappropriate proliferation of cells that have failed to exit the cell cycle....

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Detalhes bibliográficos
Main Authors: Nicolay, Brandon N., Frolov, Maxim V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542417/
https://ncbi.nlm.nih.gov/pubmed/18833298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000205
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