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Hexon Modification to Improve the Activity of Oncolytic Adenovirus Vectors against Neoplastic and Stromal Cells in Pancreatic Cancer

Primary pancreatic carcinoma has an unfavourable prognosis and standard treatment strategies mostly fail in advanced cases. Virotherapy might overcome this resistance to current treatment modalities. However, data from clinical studies with oncolytic viruses, including replicating adenoviral (Ad) ve...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lucas, Tanja, Benihoud, Karim, Vigant, Frédéric, Schmidt, Christoph Q. Andreas, Bachem, Max G., Simmet, Thomas, Kochanek, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332860/
https://ncbi.nlm.nih.gov/pubmed/25692292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117254
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