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Expanded Anticancer Therapeutic Window of Hexon-modified Oncolytic Adenovirus
One of the significant hurdles toward safe and efficacious systemic treatment of cancer with oncolytic adenoviruses (Ads) is dose-limiting hepatotoxicity that prevents the increase of a therapeutic dose. In this study, we expanded the therapeutic window of oncolytic serotype 5 Ad (Ad5) by a genetic...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814381/ https://ncbi.nlm.nih.gov/pubmed/19755961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.217 |
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