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Understanding the Hysteresis Loop Conundrum in Pharmacokinetic / Pharmacodynamic Relationships

Hysteresis loops are phenomena that sometimes are encountered in the analysis of pharmacokinetic and pharmacodynamic relationships spanning from pre-clinical to clinical studies. When hysteresis occurs it provides insight into the complexity of drug action and disposition that can be encountered. Hy...

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Détails bibliographiques
Publié dans:J Pharm Pharm Sci
Auteurs principaux: Louizos, Christopher, Yáñez, Jaime A., Forrest, Laird, Davies, Neal M.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332569/
https://ncbi.nlm.nih.gov/pubmed/24735761
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