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Pharmacokinetic and Toxicodynamic Characterization of a Novel Doxorubicin Derivative

Doxorubicin (Dox) is an effective anti-cancer medication with poor oral bioavailability and systemic toxicities. DoxQ was developed by conjugating Dox to the lymphatically absorbed antioxidant quercetin to improve Dox’s bioavailability and tolerability. The purpose of this study was to characterize...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Alrushaid, Samaa, Sayre, Casey L., Yáñez, Jaime A., Forrest, M. Laird, Senadheera, Sanjeewa N., Burczynski, Frank J., Löbenberg, Raimar, Davies, Neal M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620576/
https://ncbi.nlm.nih.gov/pubmed/28902176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics9030035
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