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Mechanistically elucidating the in vitro safety and efficacy of a novel doxorubicin derivative
Doxorubicin is an effective anticancer drug; however, it is cardiotoxic and has poor oral bioavazilability. Quercetin is a plant-based flavonoid with inhibitory effects on P-glycoprotein (P-gp) and CYP3A4 and also antioxidant properties. To mitigate these therapeutic barriers, DoxQ, a novel derivati...
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| 出版年: | Drug Deliv Transl Res |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5522622/ https://ncbi.nlm.nih.gov/pubmed/28462502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-017-0379-2 |
| タグ: |
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