Ovalbumin sensitization of guinea pig at birth prevents the ontogenetic decrease in airway smooth muscle responsiveness

Airway smooth muscle (ASM) displays a hyperresponsive phenotype at young age and becomes less responsive in adulthood. We hypothesized that allergic sensitization, which causes ASM hyperresponsiveness and typically occurs early in life, prevents the ontogenetic loss of the ASM hyperresponsive phenot...

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Dettagli Bibliografici
Pubblicato in:Physiol Rep
Autori principali: Chitano, Pasquale, Wang, Lu, Degan, Simone, Worthington, Charles L., Pozzato, Valeria, Hussaini, Syed H., Turner, Wesley C., Dorscheid, Delbert R., Murphy, Thomas M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley Periodicals, Inc. 2014
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332219/
https://ncbi.nlm.nih.gov/pubmed/25501429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12241
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