Ovalbumin sensitization of guinea pig at birth prevents the ontogenetic decrease in airway smooth muscle responsiveness

Airway smooth muscle (ASM) displays a hyperresponsive phenotype at young age and becomes less responsive in adulthood. We hypothesized that allergic sensitization, which causes ASM hyperresponsiveness and typically occurs early in life, prevents the ontogenetic loss of the ASM hyperresponsive phenot...

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Detalles Bibliográficos
Publicado en:Physiol Rep
Main Authors: Chitano, Pasquale, Wang, Lu, Degan, Simone, Worthington, Charles L., Pozzato, Valeria, Hussaini, Syed H., Turner, Wesley C., Dorscheid, Delbert R., Murphy, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado: Wiley Periodicals, Inc. 2014
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332219/
https://ncbi.nlm.nih.gov/pubmed/25501429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12241
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