Ovalbumin sensitization of guinea pig at birth prevents the ontogenetic decrease in airway smooth muscle responsiveness

Airway smooth muscle (ASM) displays a hyperresponsive phenotype at young age and becomes less responsive in adulthood. We hypothesized that allergic sensitization, which causes ASM hyperresponsiveness and typically occurs early in life, prevents the ontogenetic loss of the ASM hyperresponsive phenot...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Chitano, Pasquale, Wang, Lu, Degan, Simone, Worthington, Charles L., Pozzato, Valeria, Hussaini, Syed H., Turner, Wesley C., Dorscheid, Delbert R., Murphy, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332219/
https://ncbi.nlm.nih.gov/pubmed/25501429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12241
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