Ovalbumin sensitization of guinea pig at birth prevents the ontogenetic decrease in airway smooth muscle responsiveness

Airway smooth muscle (ASM) displays a hyperresponsive phenotype at young age and becomes less responsive in adulthood. We hypothesized that allergic sensitization, which causes ASM hyperresponsiveness and typically occurs early in life, prevents the ontogenetic loss of the ASM hyperresponsive phenot...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Physiol Rep
Prif Awduron: Chitano, Pasquale, Wang, Lu, Degan, Simone, Worthington, Charles L., Pozzato, Valeria, Hussaini, Syed H., Turner, Wesley C., Dorscheid, Delbert R., Murphy, Thomas M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Wiley Periodicals, Inc. 2014
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332219/
https://ncbi.nlm.nih.gov/pubmed/25501429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12241
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