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Insulin resistance and muscle insulin receptor substrate‐1 serine hyperphosphorylation

Insulin resistance in metabolic syndrome subjects is profound in spite of muscle insulin receptor and insulin‐responsive glucose transporter (GLUT4) expression being nearly normal. Insulin receptor tyrosine kinase phosphorylation of insulin receptor substrate‐1 (IRS‐1) at Tyr896 is a necessary step...

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Dades bibliogràfiques
Publicat a:Physiol Rep
Autors principals: Stuart, Charles A., Howell, Mary E. A., Cartwright, Brian M., McCurry, Melanie P., Lee, Michelle L., Ramsey, Michael W., Stone, Michael H.
Format: Artigo
Idioma:Inglês
Publicat: Wiley Periodicals, Inc. 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332214/
https://ncbi.nlm.nih.gov/pubmed/25472611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12236
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