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Insulin resistance and muscle insulin receptor substrate‐1 serine hyperphosphorylation

Insulin resistance in metabolic syndrome subjects is profound in spite of muscle insulin receptor and insulin‐responsive glucose transporter (GLUT4) expression being nearly normal. Insulin receptor tyrosine kinase phosphorylation of insulin receptor substrate‐1 (IRS‐1) at Tyr896 is a necessary step...

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Detalles Bibliográficos
Publicado en:Physiol Rep
Autores principales: Stuart, Charles A., Howell, Mary E. A., Cartwright, Brian M., McCurry, Melanie P., Lee, Michelle L., Ramsey, Michael W., Stone, Michael H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley Periodicals, Inc. 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332214/
https://ncbi.nlm.nih.gov/pubmed/25472611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12236
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