Insulin resistance and muscle insulin receptor substrate‐1 serine hyperphosphorylation

Insulin resistance in metabolic syndrome subjects is profound in spite of muscle insulin receptor and insulin‐responsive glucose transporter (GLUT4) expression being nearly normal. Insulin receptor tyrosine kinase phosphorylation of insulin receptor substrate‐1 (IRS‐1) at Tyr896 is a necessary step...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Physiol Rep
Prif Awduron: Stuart, Charles A., Howell, Mary E. A., Cartwright, Brian M., McCurry, Melanie P., Lee, Michelle L., Ramsey, Michael W., Stone, Michael H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Wiley Periodicals, Inc. 2014
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332214/
https://ncbi.nlm.nih.gov/pubmed/25472611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12236
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