Insulin resistance and muscle insulin receptor substrate‐1 serine hyperphosphorylation

Insulin resistance in metabolic syndrome subjects is profound in spite of muscle insulin receptor and insulin‐responsive glucose transporter (GLUT4) expression being nearly normal. Insulin receptor tyrosine kinase phosphorylation of insulin receptor substrate‐1 (IRS‐1) at Tyr896 is a necessary step...

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Dettagli Bibliografici
Pubblicato in:Physiol Rep
Autori principali: Stuart, Charles A., Howell, Mary E. A., Cartwright, Brian M., McCurry, Melanie P., Lee, Michelle L., Ramsey, Michael W., Stone, Michael H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley Periodicals, Inc. 2014
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332214/
https://ncbi.nlm.nih.gov/pubmed/25472611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12236
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