Lanean...

Testing the limits of rational design by engineering pH sensitivity into membrane active peptides

In this work, we sought to rationally design membrane active peptides that are triggered by low pH to form macromolecular-sized pores in lipid bilayers. Such peptides could have broad utility in biotechnology and in nanomedicine as cancer therapeutics or drug delivery vehicles that promote release o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochim Biophys Acta
Egile Nagusiak: Wiedman, Gregory, Wimley, William C., Hristova, Kalina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331263/
https://ncbi.nlm.nih.gov/pubmed/25572997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2014.12.023
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!