Pioglitazone restores phagocyte mitochondrial oxidants and bactericidal capacity in Chronic Granulomatous Disease

BACKGROUND: Deficient production of reactive oxygen species (ROS) by the phagocyte NADPH oxidase in Chronic Granulomatous Disease (CGD) results in susceptibility to certain pathogens secondary to impaired oxidative killing and mobilization of other phagocyte defenses. PPARγ agonists including piogli...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Allergy Clin Immunol
Main Authors: Fernandez-Boyanapalli, Ruby F., Frasch, S. Courtney, Thomas, Stacey M., Malcolm, Kenneth C., Nicks, Michael, Harbeck, Ronald J., Jakubzick, Claudia V., Nemenoff, Raphael, Henson, Peter M., Holland, Steven M., Bratton, Donna L.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331116/
https://ncbi.nlm.nih.gov/pubmed/25498313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.10.034
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker