Pioglitazone restores phagocyte mitochondrial oxidants and bactericidal capacity in Chronic Granulomatous Disease

BACKGROUND: Deficient production of reactive oxygen species (ROS) by the phagocyte NADPH oxidase in Chronic Granulomatous Disease (CGD) results in susceptibility to certain pathogens secondary to impaired oxidative killing and mobilization of other phagocyte defenses. PPARγ agonists including piogli...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Allergy Clin Immunol
Main Authors: Fernandez-Boyanapalli, Ruby F., Frasch, S. Courtney, Thomas, Stacey M., Malcolm, Kenneth C., Nicks, Michael, Harbeck, Ronald J., Jakubzick, Claudia V., Nemenoff, Raphael, Henson, Peter M., Holland, Steven M., Bratton, Donna L.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331116/
https://ncbi.nlm.nih.gov/pubmed/25498313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.10.034
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki