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Downregulation of XPF–ERCC1 enhances cisplatin efficacy in cancer cells
Bulky cisplatin lesions are repaired primarily by nucleotide excision repair (NER), in which the structure specific endonuclease XPF–ERCC1 is a critical component. It is now known that the XPF–ERCC1 complex has repair functions beyond NER and plays a role in homologous recombination (HR). It has bee...
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| Publicado no: | DNA Repair (Amst) |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4331052/ https://ncbi.nlm.nih.gov/pubmed/20418188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.03.010 |
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