GPR124 Functions as a WNT7-Specific Co-Activator of Canonical β-Catenin Signaling

G-protein coupled receptor 124 (GPR124) is an orphan receptor in the adhesion family of GPCRs and previous global or endothelial-specific disruption of Gpr124 in mice led to defective CNS angiogenesis and blood brain barriergenesis. Similar developmental defects were observed following dual deletion...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Posokhova, Ekaterina, Shukla, Animesh, Seaman, Steven, Volate, Suresh, Hilton, Mary Beth, Wu, Bofan, Morris, Holly, Swing, Deborah A., Zhou, Ming, Zudaire, Enrique, Rubin, Jeffrey S., St. Croix, Brad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331012/
https://ncbi.nlm.nih.gov/pubmed/25558062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.12.020
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