Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis

Despite the critical role of endothelial Wnt/β-catenin signaling during central nervous system (CNS) vascularization, how endothelial cells sense and respond to specific Wnt ligands and what aspects of the multistep process of intra-cerebral blood vessel morphogenesis are controlled by these angioge...

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Veröffentlicht in:eLife
Hauptverfasser: Vanhollebeke, Benoit, Stone, Oliver A, Bostaille, Naguissa, Cho, Chris, Zhou, Yulian, Maquet, Emilie, Gauquier, Anne, Cabochette, Pauline, Fukuhara, Shigetomo, Mochizuki, Naoki, Nathans, Jeremy, Stainier, Didier YR
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2015
Schlagworte:
Developmental Biology and Stem Cells
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456509/
https://ncbi.nlm.nih.gov/pubmed/26051822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06489
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