Vascular Endothelial-Cadherin Stabilizes at Cell–Cell Junctions by Anchoring to Circumferential Actin Bundles through α- and β-Catenins in Cyclic AMP-Epac-Rap1 Signal-activated Endothelial Cells

Vascular endothelial (VE)-cadherin is a cell–cell adhesion molecule involved in endothelial barrier functions. Previously, we reported that cAMP-Epac-Rap1 signal enhances VE-cadherin–dependent cell adhesion. Here, we further scrutinized how cAMP-Epac-Rap1 pathway promotes stabilization of VE-cadheri...

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Main Authors: Noda, Kazuomi, Zhang, Jianghui, Fukuhara, Shigetomo, Kunimoto, Satoshi, Yoshimura, Michihiro, Mochizuki, Naoki
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2010
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820423/
https://ncbi.nlm.nih.gov/pubmed/20032304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-07-0580
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