Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization

Reorganization of the actin cytoskeleton is responsible for dynamic regulation of endothelial cell (EC) barrier function. Circumferential actin bundles (CAB) promote formation of linear adherens junctions (AJs) and tightening of EC junctions, whereas formation of radial stress fibers (RSF) connected...

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Bibliographische Detailangaben
Hauptverfasser: Ando, Koji, Fukuhara, Shigetomo, Moriya, Takahiro, Obara, Yutaro, Nakahata, Norimichi, Mochizuki, Naoki
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2013
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776352/
https://ncbi.nlm.nih.gov/pubmed/24019534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201301115
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