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Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization
Reorganization of the actin cytoskeleton is responsible for dynamic regulation of endothelial cell (EC) barrier function. Circumferential actin bundles (CAB) promote formation of linear adherens junctions (AJs) and tightening of EC junctions, whereas formation of radial stress fibers (RSF) connected...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3776352/ https://ncbi.nlm.nih.gov/pubmed/24019534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201301115 |
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