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Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization

Reorganization of the actin cytoskeleton is responsible for dynamic regulation of endothelial cell (EC) barrier function. Circumferential actin bundles (CAB) promote formation of linear adherens junctions (AJs) and tightening of EC junctions, whereas formation of radial stress fibers (RSF) connected...

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Détails bibliographiques
Auteurs principaux: Ando, Koji, Fukuhara, Shigetomo, Moriya, Takahiro, Obara, Yutaro, Nakahata, Norimichi, Mochizuki, Naoki
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776352/
https://ncbi.nlm.nih.gov/pubmed/24019534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201301115
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