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Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization

Reorganization of the actin cytoskeleton is responsible for dynamic regulation of endothelial cell (EC) barrier function. Circumferential actin bundles (CAB) promote formation of linear adherens junctions (AJs) and tightening of EC junctions, whereas formation of radial stress fibers (RSF) connected...

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Detalhes bibliográficos
Main Authors: Ando, Koji, Fukuhara, Shigetomo, Moriya, Takahiro, Obara, Yutaro, Nakahata, Norimichi, Mochizuki, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776352/
https://ncbi.nlm.nih.gov/pubmed/24019534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201301115
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