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Molecular insights into Adgra2/Gpr124 and Reck intracellular trafficking
Adgra2, formerly known as Gpr124, is a key regulator of cerebrovascular development in vertebrates. Together with the GPI-anchored glycoprotein Reck, this adhesion GPCR (aGPCR) stimulates Wnt7-dependent Wnt/β-catenin signaling to promote brain vascular invasion in an endothelial cell-autonomous mann...
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| Pubblicato in: | Biol Open |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Ltd
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5200908/ https://ncbi.nlm.nih.gov/pubmed/27979830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.021287 |
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