Dynamic loading and redistribution of the Mcm2-7 helicase complex through the cell cycle

Eukaryotic replication origins are defined by the ORC-dependent loading of the Mcm2-7 helicase complex onto chromatin in G1. Paradoxically, there is a vast excess of Mcm2-7 relative to ORC assembled onto chromatin in G1. These excess Mcm2-7 complexes exhibit little co-localization with ORC or replic...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Powell, Sara K, MacAlpine, Heather K, Prinz, Joseph A, Li, Yulong, Belsky, Jason A, MacAlpine, David M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BlackWell Publishing Ltd 2015
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331006/
https://ncbi.nlm.nih.gov/pubmed/25555795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488307
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