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Intrinsic biocontainment: Multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes

Biocontainment may be required in a wide variety of situations such as work with pathogens, field release applications of engineered organisms, and protection of intellectual properties. Here, we describe the control of growth of the brewer’s yeast, Saccharomyces cerevisiae, using both transcription...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cai, Yizhi, Agmon, Neta, Choi, Woo Jin, Ubide, Alba, Stracquadanio, Giovanni, Caravelli, Katrina, Hao, Haiping, Bader, Joel S., Boeke, Jef D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330768/
https://ncbi.nlm.nih.gov/pubmed/25624482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424704112
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