Inositol pyrophosphates promote tumor growth and metastasis by antagonizing liver kinase B1

The inositol pyrophosphates, molecular messengers containing an energetic pyrophosphate bond, impact a wide range of biologic processes. They are generated primarily by a family of three inositol hexakisphosphate kinases (IP6Ks), the principal product of which is diphosphoinositol pentakisphosphate...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rao, Feng, Xu, Jing, Fu, Chenglai, Cha, Jiyoung Y., Gadalla, Moataz M., Xu, Risheng, Barrow, James C., Snyder, Solomon H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330756/
https://ncbi.nlm.nih.gov/pubmed/25617365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424642112
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