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Differential regulation of the Hippo pathway by adherens junctions and apical–basal cell polarity modules

Adherens junctions (AJs) and cell polarity complexes are key players in the establishment and maintenance of apical–basal cell polarity. Loss of AJs or basolateral polarity components promotes tumor formation and metastasis. Recent studies in vertebrate models show that loss of AJs or loss of the ba...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Yang, Chih-Chao, Graves, Hillary K., Moya, Ivan M., Tao, Chunyao, Hamaratoglu, Fisun, Gladden, Andrew B., Halder, Georg
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330745/
https://ncbi.nlm.nih.gov/pubmed/25624491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420850112
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