Pharmacogenomics of Hypertension: A Genome‐Wide, Placebo‐Controlled Cross‐Over Study, Using Four Classes of Antihypertensive Drugs

BACKGROUND: Identification of genetic markers of antihypertensive drug responses could assist in individualization of hypertension treatment. METHODS AND RESULTS: We conducted a genome‐wide association study to identify gene loci influencing the responsiveness of 228 male patients to 4 classes of an...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Hiltunen, Timo P., Donner, Kati M., Sarin, Antti‐Pekka, Saarela, Janna, Ripatti, Samuli, Chapman, Arlene B., Gums, John G., Gong, Yan, Cooper‐DeHoff, Rhonda M., Frau, Francesca, Glorioso, Valeria, Zaninello, Roberta, Salvi, Erika, Glorioso, Nicola, Boerwinkle, Eric, Turner, Stephen T., Johnson, Julie A., Kontula, Kimmo K.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330076/
https://ncbi.nlm.nih.gov/pubmed/25622599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001521
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