Pharmacogenomics of Hypertension: A Genome‐Wide, Placebo‐Controlled Cross‐Over Study, Using Four Classes of Antihypertensive Drugs

BACKGROUND: Identification of genetic markers of antihypertensive drug responses could assist in individualization of hypertension treatment. METHODS AND RESULTS: We conducted a genome‐wide association study to identify gene loci influencing the responsiveness of 228 male patients to 4 classes of an...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Hiltunen, Timo P., Donner, Kati M., Sarin, Antti‐Pekka, Saarela, Janna, Ripatti, Samuli, Chapman, Arlene B., Gums, John G., Gong, Yan, Cooper‐DeHoff, Rhonda M., Frau, Francesca, Glorioso, Valeria, Zaninello, Roberta, Salvi, Erika, Glorioso, Nicola, Boerwinkle, Eric, Turner, Stephen T., Johnson, Julie A., Kontula, Kimmo K.
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330076/
https://ncbi.nlm.nih.gov/pubmed/25622599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001521
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