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Single-step generation of rabbits carrying a targeted allele of the tyrosinase gene using CRISPR/Cas9
Targeted genome editing of nonrodent mammalian species has provided the potential for highly accurate interventions into gene function in humans and the generation of useful animal models of human diseases. Here we show successful clustered regularly interspaced short palindromic repeat (CRISPR) and...
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| Publié dans: | Exp Anim |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Japanese Association for Laboratory Animal Science
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329513/ https://ncbi.nlm.nih.gov/pubmed/25195632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.14-0034 |
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